Adverse Effects of e-Cigarette Exposures

Introduction:
This text is a summary of a study on the adverse effects of e-cigarette exposures, specifically focusing on the experience of a statewide poison system. The study aims to provide information on the toxicity of electronic cigarettes (ECIGs) and the resulting health effects of their use.

Key Points:

* The study identified 35 cases of ECIG exposures from 2010 to 2012, with the number of cases increasing each year.
* The majority of exposures were in children under 8 years old, with symptoms including vomiting and coughing.
* Adults reported adverse effects from normal use, including nausea, vomiting, coughing, chest pain, confusion, and palpitations.
* Leaking cartridges resulted in dermal and ocular exposures, causing mild irritation.
* ECIG products are currently unregulated in the United States, making it easy for children and young adults to access them.
* The estimated oral toxic dose for nicotine is 615 0.5-1 mg/kg, and most ECIG cartridges contain 0.15-1 ml of liquid.
* The study found that the risk for significant poisoning following an oral exposure to an ECIG cartridge appears low.
* The study notes that more concentrated, highly palatable products are currently available and may pose significant health risks from acute exposures.

Main Message:
The main message of this text is that while ECIG exposure calls to poison centers are increasing, short-term adverse effects and accidental exposures to ECIG cartridges are unlikely to result in serious toxicity. However, clinicians should be aware of the availability of more concentrated, highly palatable products that may pose significant health risks from acute exposures. The study emphasizes the need for regulation and standardization of ECIG ingredients to ensure the safety and health of users.

Cantrell, F. Lee. “Adverse Effects of E-Cigarette Exposures.” Journal of Community Health 39, no. 3 (June 2014): 614–16. https://doi.org/10.1007/s10900-013-9807-5.