Summary
Introduction:
This text provides an analysis of the relationship between e-cigarette use and periodontal health, specifically examining the levels of certain biomarkers in the gingival crevicular fluid (GCF) of e-cigarette and cigarette smokers. The study also utilizes Raman spectroscopy to characterize the GCF samples.
Key Points:
* The study included 60 healthy men, 30 of whom were e-cigarette smokers and 30 of whom were cigarette smokers.
* Clinical periodontal parameters, including plaque score, bleeding on probing, probing depth, and clinical attachment loss, were assessed at baseline, 3 months, and 6 months.
* GCF samples were collected from healthy and periodontitis sites in both e-cigarette and cigarette smokers at the same time points.
* The levels of MMP-8 and CTX in the GCF samples were quantified using ELISa.
* Raman spectroscopy was used to characterize the GCF samples and identify specific spectral signatures.
* The study found that both e-cigarette and cigarette smokers showed worse periodontal parameters in periodontitis sites compared to healthy sites, but cigarette smokers had higher levels of MMP-8 and CTX in the GCF.
* The Raman spectroscopy analysis showed differences in the intensity and position of peaks in the GCF samples from e-cigarette and cigarette smokers.
Main Message:
This study suggests that e-cigarette use may have negative effects on periodontal health, with higher levels of MMP-8 and CTX in the GCF of e-cigarette smokers compared to healthy controls. The use of Raman spectroscopy to characterize the GCF samples provides a potential diagnostic tool for periodontal disease. Further research is needed to confirm these findings and explore the underlying mechanisms.
Citation
akram Z, aati S, alrahlah a, Vohra F, Fawzy a. Longitudinal evaluation of clinical, spectral and tissue degradation biomarkers in progression of periodontitis among cigarette and electronic cigarette smokers. Journal of dentistry. 2021;109:103678. doi:10.1016/j.jdent.2021.103678
