Effect of electronic cigarette aerosol exposure during gestation and lactation on learning and memory of adult male offspring rats.

Relative to exposure to fresh air, exposure to ECIG aerosol during gestation/lactation impaired long-term memory in adult offspring (P<0.05). This impairment was associated with increased activity of superoxide dismutase in the hippocampus (P<0.05). BDNF and the other tested oxidative stress biomarkers were not affected by ECIG aerosol exposure (p>0.05). Use of ENDS during pregnancy effected the long-term memory of offspring.

al-Sawalha N, alzoubi K, Khabour O, et al. Effect of electronic cigarette aerosol exposure during gestation and lactation on learning and memory of adult male offspring rats. Physiology & behavior. 2020;221:112911. doi:10.1016/j.physbeh.2020.112911