Summary
Introduction:
This text is a summary of a research study that investigates the effects of electronic cigarette (e-cig) and cigarette smoking on periodontal health. The study compares the clinical periodontal parameters, gingival crevicular fluid (GCF) samples, and the levels of biomarkers MMP-8 and CTX in e-cig and cigarette smokers. The study also analyzes the GCF samples using Raman spectroscopy to determine specific spectral signatures for differentiating between healthy and diseased tissues.
Key points:
* The study included 60 healthy men (30 e-cig smokers and 30 cigarette smokers) with a mean age of 35.74 ±14.52 years.
* The participants were monitored at baseline, 3 months, and 6 months. Clinical periodontal parameters, GCF samples, and biomarkers MMP-8 and CTX levels were measured at each time point.
* The study found that cigarette smokers showed worse periodontal parameters compared to e-cig smokers.
* MMP-8 and CTX levels were significantly correlated with probing depth and clinical attachment loss in both e-cig and cigarette smokers.
* Raman spectroscopy analysis revealed specific spectral signatures for differentiating between healthy and diseased tissues in both e-cig and cigarette smokers.
* The aUC by ROC analysis showed that smoking, MMP-8, and CTX were the highest predictors of clinical attachment loss in both e-cig and cigarette smokers.
* The concentration of MMP-8 and CTX was significantly higher in periodontitis sites compared to healthy sites in both e-cig and cigarette smokers.
Main message:
The study provides evidence that e-cig smoking has negative effects on periodontal health, although not as severe as cigarette smoking. The study highlights the importance of monitoring clinical periodontal parameters, GCF samples, and biomarkers such as MMP-8 and CTX in assessing periodontal health in e-cig and cigarette smokers. The use of Raman spectroscopy analysis provides a potential tool for differentiating between healthy and diseased tissues, which could aid in the early detection and prevention of periodontal disease in e-cig and cigarette smokers.
Citation
ali N, Xavier J, Engur M, Pv M, Bernardino de la Serna J. The impact of e-cigarette exposure on different organ systems: a review of recent evidence and future perspectives. Journal of hazardous materials. 2023;457:131828. doi:10.1016/j.jhazmat.2023.131828
