The Identification of Drugs of abuse in E-Cigarette Samples Seized in Dubai between 2016 and 2020.

Introduction:
This text presents the results of a longitudinal study evaluating the periodontal health of cigarette smokers, electronic cigarette (e-cig) users, and non-smokers. The study also analyzed gingival crevicular fluid (GCF) samples using Raman spectroscopy to identify key functional groups. additionally, the study measured MMP-8 and CTX levels in the GCF to determine if they are predictive factors for attachment loss in periodontitis sites.

Key Points:

* The study included 30 cigarette smokers, 30 e-cig users, and 30 non-smokers.
* Participants were monitored at baseline, 3 months, and 6 months.
* GCF samples were collected to measure MMP-8 and CTX levels.
* Raman spectroscopy was used to identify key functional groups in the GCF.
* Cigarette smokers showed higher attachment loss than e-cig users and non-smokers.
* MMP-8 and CTX levels were significantly correlated with probing depth and clinical attachment loss in both e-cig and cigarette smokers.
* Raman spectroscopy identified differences in spectral signatures between healthy and diseased tissues.

Main Message:
The study suggests that cigarette smoking is a significant risk factor for periodontal disease and that MMP-8 and CTX levels may be useful predictive biomarkers for attachment loss in periodontitis sites. The use of Raman spectroscopy to analyze GCF samples shows promise as a non-invasive diagnostic tool for periodontal disease. however, further research is needed to validate these findings and establish clinical guidelines for their use. Overall, the study highlights the importance of promoting smoking cessation and developing effective diagnostic and treatment strategies for periodontal disease.

almazrouei ES, Bintamim aa, Khalil SEa, alremeithi R, Gewily S. The Identification of Drugs of abuse in E-Cigarette Samples Seized in Dubai between 2016 and 2020.; 2022:111233.