adding Data From 2015 Strengthens the association Between E-Cigarette Use and Myocardial Infarction.

Introduction:
This text summarizes a response from authors Talal alzahrani and Stanton Glantz to criticisms of their study on the association between e-cigarette use and myocardial infarction. They address the use of population weights and the analytic approach in their study, and provide additional analyses using data from 2015. They also discuss the implications of their findings and the relevance of including dual users in the analysis.

Key Points:

* The authors clarify that they did not use population weights in the descriptive statistics, but did use them in the logistic regression analyses to account for the complex survey design.
* The authors used a different weight variable than Manderski et al. because they analyzed variables from the adult sample, while Manderski et al. analyzed family and person data.
* The authors used age in 10-year intervals, while Manderski et al. used age as a continuous variable, leading to small differences in the results.
* The authors treated BMI=99.99 as a real value, but have updated the results treating it as a missing value.
* The authors found that the 2015 data reveal significantly increased odds of having had a myocardial infarction for both some-day and everyday e-cigarette use.
* The authors argue that it is not necessary to perform an analysis of e-cigarette use among people who never smoke to assess an independent association with myocardial infarction.
* The authors mention that three recent studies have confirmed their results.

Main Message:
The authors strongly defend their study and its findings, emphasizing that the use of population weights and the analytic approach do not affect the overall conclusion of a significant association between e-cigarette use and myocardial infarction. They also highlight the importance of including dual users in the analysis and the confirmation of their results by three recent studies. The inclusion of the 2015 data strengthens the association and provides further evidence of the risks associated with e-cigarette use.

alzahrani T, Glantz Sa. adding Data From 2015 Strengthens the association Between E-Cigarette Use and Myocardial Infarction. american journal of preventive medicine. 2019;57(4):569-571. doi:10.1016/j.amepre.2019.03.008