The effect of electronic cigarettes exposure on learning and memory functions: behavioral and molecular analysis.

The study found that electronic cigarette (ECIG) aerosol exposure impairs functional memory and elicits changes in brain chemistry consistent with reduced function and oxidative stress in rats. Specifically, ECIG aerosol exposure for 4 and 12 weeks, but not 1 week, impaired both short- and long-term memory and induced reductions in hippocampal BDNF, SOD and GPx activities, and GSh/GSSG ratio. These findings suggest that regulations addressing the marketing of ECIG products are needed to stem misconceptions about use risk and to limit or eliminate ECIG use by previously nicotine-naïve individuals.

alzoubi Kh, Batran RM, al-Sawalha Na, et al. The effect of electronic cigarettes exposure on learning and memory functions: behavioral and molecular analysis. Inhalation toxicology. 2021;33(6-8):234-243. doi:10.1080/08958378.2021.1954732