Summary
The study found that in utero exposure to e-cigarette vapor, regardless of nicotine presence, leads to long-term pulmonary dysfunction and structural impairments in offspring. Specifically, female and male mice from e-cigarette vapor exposed groups had greater lung stiffness, reduced compliance, and decreased forced expiratory volume compared to the control group. additionally, lung histology revealed increased collagen deposition around the vessels/airways and in alveolar tissue, as well as goblet hyperplasia in some groups. These findings suggest that e-cigarette use during pregnancy may have detrimental effects on the respiratory health of offspring.
Citation
aslaner DM, alghothani O, Saldana Ta, et al. E-cigarette vapor exposure in utero causes long-term pulmonary effects in offspring. american journal of physiology Lung cellular and molecular physiology. 2022;323(6):L676-L682. doi:10.1152/ajplung.00233.2022
