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Pod-based e-cigarettes versus combustible cigarettes: The impact on peripheral and cerebral vascular function and subjective experiences.

Author: Ben Taleb

Year Published: 2023

Summary

Introduction:
This text provides an analysis of a research paper examining the impact of pod-based e-cigarettes versus combustible cigarettes on peripheral and cerebral vascular function and subjective experiences in adult cigarette smokers. The study aims to contribute to the understanding of the health effects of e-cigarette use.

Key Points:

* The study uses a crossover laboratory design with 19 cigarette smokers who were e-cigarette naïve.
* Participants smoked a cigarette and vaped a pod-based e-cigarette in separate sessions, and completed questions assessing subjective experiences.
* Peripheral macrovascular and microvascular function was assessed via brachial artery FMD and reactive hyperemia, while cerebral vascular function was assessed as the blood velocity response of the middle cerebral artery during hypercapnia.
* The study found that vaping a pod-based e-cigarette leads to an impairment in peripheral and cerebral vascular function while providing a reduced subjective experience compared with a cigarette among adult smokers.
* The magnitude of reduction in peripheral and cerebral vascular function was similar between conditions.
* The study concludes that these data challenge the notion that e-cigarette use is a safe and satisfactory alternative to cigarette use.

Main Message:
The main message of the study is that vaping pod-based e-cigarettes has similar negative effects on vascular function as smoking cigarettes, and therefore may not be a safe or satisfactory alternative to cigarette smoking. The study highlights the need for large longitudinal studies to assess the long-term impact of pod-based e-cigarette devices on cardiovascular and behavioral outcomes. Overall, the study adds to the growing body of evidence suggesting that e-cigarette use is not risk-free and should be approached with caution.

Citation

Ben Taleb Z, Dabroy D, akins J, et al. Pod-based e-cigarettes versus combustible cigarettes: The impact on peripheral and cerebral vascular function and subjective experiences. Tobacco induced diseases. 2023;21:71. doi:10.18332/tid/162366
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