Vaping: difference between inhalation and oral toxicology.

Introduction:
This summary will provide an overview of a letter written by Dr. Sherwood Burge, an expert in regulatory matters, regarding the safety of vaping. Dr. Burge challenges the position of UK experts who claim that vaping is relatively safe compared to smoking cigarettes. The letter highlights the differences between inhalation and oral toxicology and the potential risks associated with inulating certain substances.

Key Points:

* The UK experts' claim that most flavors used in vaping are safe when inhaled is flawed.
* The commonest cause of occupational asthma in Europe is inhaled flour, and thiamine can cause asthma when inhaled, despite being an essential element in food.
* Most vitamins have the chemical structure of respiratory allergens.
* The safety of vaping is based on theoretical grounds, rather than observational science.
* There are differences between inhalation and oral toxicology that should be taken into account.
* The promotion of vaping should consider the potential risks associated with inhaling certain substances.
* The author declares no competing interests.

Main Message:
Dr. Burge emphasizes the importance of understanding the differences between inhalation and oral toxicology when evaluating the safety of vaping. he argues that the theoretical safety of vaping is not sufficient and that potential risks associated with inhaling certain substances should be taken into account. The letter serves as a reminder that promoting vaping should be done with caution and that further research is needed to fully understand the potential risks associated with vaping.

Burge S. Vaping: difference between inhalation and oral toxicology. BMJ (Clinical research ed). 2019;367:1. doi:10.1136/bmj.l6358