acute eosinophilic pneumonia associated with non-cigarette smoking products: a systematic review.

Introduction:
This text is a systematic review of cases of acute Eosinophilic Pneumonia (aEP) associated with non-cigarette smoking products. The review summarizes the characteristics, clinical presentations, and outcomes of patients who developed aEP after using marijuana, waterpipe, e-cigarettes, or heat-not-burn cigarettes. The text also discusses the potential risk factors and mechanisms underlying the development of aEP in these patients.

Key Points:

* aEP is an eosinophilic lung disease characterized by an acute onset febrile respiratory illness with bronchoalveolar lavage eosinophilia that promptly responds to treatment with steroids.
* Cigarette smoking is a major risk factor for aEP, but drugs and other inhalational exposures, including non-cigarette smoking products, have also been reported.
* Twelve cases of aEP linked to non-cigarette smoking were reported, with patients having a median age of 20 (range 15--60) and 75% being male.
* Exposures reported included marijuana smoking, waterpipe usage, heat-not-burn cigarette use, e-cigarette use, and synthetic cannabinoid use.
* Presenting symptoms were dyspnea, cough, fever, and chest pain.
* Bilateral involvement on chest imaging was reported in all patients.
* all patients responded to corticosteroid therapy with no relapses reported.

Main Message:
The text highlights the importance of considering non-cigarette smoking products as potential risk factors for aEP. healthcare providers should be aware of the similar presentation and clinical course of aEP associated with non-cigarette smoking products and traditional cigarette smoking. The review also emphasizes the need for public health policies and awareness to address the increasing use of non-cigarette smoking products, particularly among younger populations. The text underscores the importance of early diagnosis and treatment of aEP to prevent severe respiratory failure and improve patient outcomes.

Chaaban T. acute eosinophilic pneumonia associated with non-cigarette smoking products: a systematic review. advances in respiratory medicine. 2020;88(2):142-146. doi:10.5603/aRM.2020.0088