health risks of dual use of electronic and combustible cigarettes: exposure to acrylamide and glycidamide.

Introduction:
This text provides an analysis of the exposure risks of acrylamide (aa) and glycidamide (Ga) in relation to different smoking status (smoking vs nonsmoking) in a cross-sectional study of 1657 participants from the United States National health and Nutrition Examination Survey (NhaNES) conducted between 2015 and 2016. The study aimed to investigate the exposure risks of aa and Ga in relation to different smoking status (smoking vs nonsmoking) by analyzing hbaa and hbGa concentrations in different smoking groups (nonsmokers, cigarettes smoking only, e-cigarettes smoking only, and dual users).

Key Points:

* The study found that dual users had the highest hbaa and hbGa concentrations (median [interquartile range], 83.75 [53.28--128.25] pmol/ghb and 61.20 [40.73--89.78] pmol/ghb, respectively).
* There was a positive association between the use of e-cigarettes and the hbaa concentration (standardized β coefficient, 0.316; P <0.001).
* The standardized β coefficients of hbaa and hbGa between the combustible cigarette smokers and nonsmokers in the fully adjusted model were 0.312 and 0.255 (both P <0.001) and those between the dual users and nonsmokers in the fully adjusted model were 0.396 and 0.342, respectively (both P <0.001).
* The study population consisted of participants from the NhaNES database from 2015 to 2016 who had hbaa and hbGa concentrations measured.
* Participants were divided into four groups: cigarette smoking only, e-cigarette smoking only, dual users, and nonsmokers.
* The study analyzed the exposure risk of harmful substances in patients with different smoking status.
* The study found that dual users of combustible cigarettes and e-cigarettes have the highest measures of hbaa and hbGa.

Main Message:
The main message of this text is that e-cigarette users are exposed to aa, and users of both combustible and e-cigarettes have highest measures of hbaa and hbGa. The study highlights the importance of communicating the coexposure risks of combustible cigarettes and e-cigarettes to the public, and the need for further studies to aid in health promotion. The study also emphasizes the importance of promoting smoking cessation as a crucial intervention to maintain the health of smokers and nonsmokers, and to lead to great financial savings.

Cheng YW, hung CC, Kao TW, Chen WL. health risks of dual use of electronic and combustible cigarettes: exposure to acrylamide and glycidamide. Polish archives of internal medicine. 2022;132(1). doi:10.20452/pamw.16103