Summary
Introduction:
This text provides an analysis of a study that identified and characterized a new synthetic cannabinoid, aDB-BRIN aCa, found in seized e-cigarette liquids. The study used various analytical techniques such as GC-MS, hPLC-qTOF-MS/MS, and NMR to determine the structure and concentration of the compound.
Key Points:
* aDB-BRIN aCa is a new synthetic cannabinoid from the indazole-3-carboxamide family.
* The compound was identified in seized e-cigarette liquids using GC-MS, hPLC-qTOF-MS/MS, and NMR.
* The concentration of aDB-BRIN aCa in the seized e-cigarette liquids was determined using ERETIC 2, a quantitative NMR method.
* aDB-BRIN aCa is a butyl indazole-3-carboxamide derivative with a bromine atom in the indazole moiety.
* The study is the first to report the analytical characterization of aDB-BRIN aCa.
* No other known synthetic cannabinoids were found in the seized e-cigarette liquids except aDB-BRIN aCa.
* aDB-BRIN aCa may pose a threat to the health of drug users due to its considerable amount in the seized e-cigarette liquids.
Main Message:
The study identifies and characterizes a new synthetic cannabinoid, aDB-BRIN aCa, found in seized e-cigarette liquids. The use of various analytical techniques enabled the determination of the compound's structure and concentration. The significant amount of aDB-BRIN aCa in the seized e-cigarette liquids may pose a health risk to drug users. Therefore, it is crucial to monitor and regulate the production and distribution of synthetic cannabinoids to protect public health.
Citation
Choi h, Kim S, Jang h, Kim hJ, Choe S. Identification of a novel bromoindazole synthetic cannabinoid analogue in seized e-cigarette liquid: aDB-BRINaCa. Forensic science international. 2022;338:111385. doi:10.1016/j.forsciint.2022.111385
