Influence of Electronic Cigarettes on antioxidant Capacity and Nucleotide Metabolites in Saliva.

Introduction:
This article examines the impact of electronic cigarettes on the antioxidant capacity of saliva, which is an essential aspect of maintaining oral health. The study compares the antioxidant capacity of saliva in e-cigarette users, traditional cigarette smokers, and non-smokers. The study's key points highlight the differences in antioxidant capacity between these groups and the correlation between uric acid and total antioxidant status (TaOS) in each group.

Key Points:

* The study involved 110 patients, including 35 e-cigarette users, 33 traditional cigarette smokers, and 42 non-smokers.
* Saliva samples were analyzed for uric acid, hypoxanthine, xanthine, TaOS, and TEaC (Trolox equivalent antioxidant capacity).
* Uric acid concentration tended to be higher in e-cigarette users, while no differences were observed in hypoxanthine and xanthine concentrations.
* TaOS values were lower in e-cigarette users and traditional cigarette smokers than in non-smokers, indicating a reduced antioxidant capacity.
* TEaC values were also lower in e-cigarette users and traditional cigarette smokers than in non-smokers.
* Statistically significant correlations were observed between uric acid and TaOS in e-cigarette users and traditional cigarette smokers.
* No statistically significant differences were observed in hypoxanthine and xanthine concentrations between e-cigarette users and traditional cigarette smokers.

Main Message:
The study's main message is that e-cigarette usage adversely affects the antioxidant capacity of saliva, to the same extent as traditional cigarette smoking. This finding is significant because it challenges the common view that e-cigarettes are less harmful than traditional cigarettes. The study highlights the need for further research to assess how these changes in antioxidant capacity may translate to oral health outcomes.

Cichońska D, Król O, Słomińska EM, et al. Influence of Electronic Cigarettes on antioxidant Capacity and Nucleotide Metabolites in Saliva. Toxics. 2021;9(10). doi:10.3390/toxics9100263