Birth Outcomes associated With E-Cigarette and Non-E-Cigarette Tobacco Product Use During Pregnancy: an Examination of PaTh Data Waves 1-5.

Introduction:
This text provides an analysis of the relationship between e-cigarette use and pregnancy outcomes using data from the Population assessment of Tobacco and health Study. The study examines the prevalence and correlates of past 30-day exclusive e-cigarette use and dual-use of e-cigarettes with other tobacco products in a sample of currently pregnant women and investigates associations between past 30-day e-cigarette and other tobacco use with pregnancy and birth outcomes.

Key Points:

* The study uses data from the Population assessment of Tobacco and health Study, which is a nationally representative, longitudinal cohort study of adults in the United States.
* The study examines the prevalence and correlates of past 30-day exclusive e-cigarette use and dual-use of e-cigarettes with other tobacco products in a sample of currently pregnant women.
* The study investigates associations between past 30-day e-cigarette and other tobacco use with pregnancy and birth outcomes.
* The study controlled for age, race/ethnicity, gestational age at baseline, and past 30-day alcohol use.
* The study found that past 30-day e-cigarette use during pregnancy was not associated with increased risk of an adverse pregnancy or birth outcome.
* The study found that past 30-day non-e-cigarette tobacco use during pregnancy was associated with a 2-fold increase in the odds of reporting an adverse birth outcome.
* The study suggests that pregnant women who use e-cigarettes may indicate an interest in quitting smoking, and healthcare providers should take this opportunity to discuss evidence-based cessation methods and other resources to facilitate quitting.

Main Message:
The study finds that e-cigarette use during pregnancy is not associated with increased risk of adverse pregnancy or birth outcomes, but past 30-day non-e-cigarette tobacco use during pregnancy was associated with a 2-fold increase in the odds of reporting an adverse birth outcome. The study suggests that pregnant women who use e-cigarettes may indicate an interest in quitting smoking, and healthcare providers should take this opportunity to discuss evidence-based cessation methods and other resources to facilitate quitting. however, the study also notes the need for further research to dissociate the impacts of exclusive e-cigarette use from dual use on pregnancy and birth outcomes, examine differences in biomarkers of exposure between e-cigarette and non-e-cigarette tobacco user groups of pregnant women, and the potential impact of biomarkers of exposure on pregnancy and birth outcomes.

Cohn aM, Elmasry h, Wild RC, et al. Birth Outcomes associated With E-Cigarette and Non-E-Cigarette Tobacco Product Use During Pregnancy: an Examination of PaTh Data Waves 1-5. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. 2023;25(3):444-452. doi:10.1093/ntr/ntac111