CORESTa Guide Number 22 Technical Guide for the Selection of appropriate Intense Vaping Regimes for E-Vapour Devices

Introduction:
This text is a technical guide published by CORESTa, an international organization for scientific research related to tobacco, that provides guidance on selecting appropriate intense vaping regimes for e-vapour devices. The guide is designed to help researchers and regulators understand how to set up aerosol generation and collection systems to evaluate e-vapour devices under intense use scenarios.

Key Points:

* The guide provides recommendations for adjusting various parameters that affect aerosol generation, such as puff duration, puff volume, puff frequency, puff profile, puff number, battery charge status, heating element or atomizer age, voltage setting, ventilation setting, and device orientation.
* Topography data from recent studies are summarized, including puff duration, puff interval, and puff volume. The literature suggests that those who vape for a shorter series of puffs have longer puff durations compared to those taking a larger series. The inter-puff interval is also impacted by series and duration of puffs.
* aerosol should be generated using a collection system capable of meeting the requirements described in CRM 81 using a pre-set puff volume and puff duration. Current commercially available instruments for aerosol generation and collection have limitations, such as maximum puff volume and duration, minimum puff frequency, and decreased number of ports available for use at extended puff durations and decreased puff frequency.
* Devices and instrument settings should result in higher aerosol generation under normal expected human usage than that observed for non-intense use. The parameters are not independent and should be based on representative intense human usage rather than the maximum extremes of each individual parameter.

Main Message:
The CORESTa guide N° 22 provides essential recommendations for researchers and regulators to evaluate e-vapour devices under intense use scenarios accurately. By adjusting the various parameters that affect aerosol generation and collection and considering topography data, researchers can set up aerosol generation and collection systems that meet the requirements described in CRM 81. Understanding the technical limitations of aerosol generation instruments and designing tests based on representative intense human usage is crucial for accurate and meaningful results.

“CORESTa Guide Number 22 Technical Guide for the Selection of appropriate Intense Vaping Regimes for E-Vapour Devices.” CORESTa, February 2018.