Pulmonary effects of e-liquid flavors: a systematic review.

The article reviews previous studies on the impact of e-cigarette flavors on lung health.
The review cites a 2014 study by L. Yin and M. Lee, which identified 460 brands of e-cigarettes, highlighting the need for product regulation. another study by Ziebarth in 1997 explored the role of bacteria in the nitrosation of drugs, which could have implications for the way we understand the effects of e-cigarettes on the body.
The document also references a 2018 study by Zahedi et al., which found that exposure to electronic cigarettes can lead to epithelial-to-mesenchymal transition in lung cancer cells. This suggests that e-cigarettes could have carcinogenic effects.
The review further cites a 2014 study by Zhu et al., which also identified a wide variety of e-cigarette brands and discussed the implications for product regulation.
The document also references two studies by hwang and Lee in 2008, which investigated the impact of cinnamaldehyde (a common e-cigarette flavoring) on toll-like receptor 4 activation. These studies suggest that certain e-cigarette flavors could have immunosuppressive effects.
Finally, the document references a 2019 report by the World health Organization on the global tobacco epidemic, which emphasizes the importance of offering help to quit tobacco use.
Overall, the document suggests that e-cigarette flavors could have a range of negative health effects on the lungs, and highlights the need for further research and product regulation.

Effah F, Taiwo B, Baines D, Bailey a, Marczylo T. Pulmonary effects of e-liquid flavors: a systematic review. Journal of toxicology and environmental health Part B, Critical reviews. 2022;25(7):343-371. doi:10.1080/10937404.2022.2124563