a review of constituents identified in e-cigarette liquids and aerosols.

Introduction:
This text provides a comprehensive review of the chemicals present in e-cigarette liquids and aerosols. The review identifies 60 compounds in e-liquids and 47 compounds in aerosols, with 22 compounds identified in both. These chemicals have the potential to cause health effects when inhaled, and further research is needed to determine their risks to humans and support evidence-based regulations and health policies.

Key Points:

* The review includes 28 articles published in English between 2013 and 2020.
* Of the 28 articles, 18 studies examined e-liquids and identified 60 constituents, while 15 studies examined aerosols and identified 47 constituents.
* Five studies examined both e-liquids and aerosols and identified 22 common chemicals present in both mediums.
* Various techniques were used for analysis, including gas chromatography-mass spectrometry, high performance liquid chromatography, and inductively coupled plasma mass spectrometry.
* Some of the identified chemicals have been labeled as harmful, toxic, or cancerous through human, animal, and cell line studies.
* E-cigarette use has risen rapidly, and there is insufficient evidence to rule out the contribution of other chemicals of concern to the recent outbreak of e-cigarette or vaping product use-associated lung injury (EVaLI).
* Further research is needed to identify the specific chemicals present in e-liquids and aerosols, understand their short- and long-term effects on human health, and implement effective regulations.

Main Message:
The review highlights the need for further research to identify and quantify the chemical compounds present in e-cigarettes, which is a vital first step in risk assessment and implementation of effective regulations. The increasing prevalence of e-cigarette use and the latest outbreaks of serious respiratory illnesses among users underscore the urgency of this research. The review also emphasizes the need to identify the mechanisms and causative constituents through further focused chemical analyses. Overall, the review contributes to the growing body of evidence on the potential health risks of e-cigarettes and supports the need for evidence-based regulations and health policies to protect public health.

Eshraghian Ea, al-Delaimy WK. a review of constituents identified in e-cigarette liquids and aerosols. Tobacco prevention & cessation. 2021;7:10. doi:10.18332/tpc/131111