Sugar and aldehyde Content in Flavored Electronic Cigarette Liquids

Introduction:
This text provides an analysis of the sugar and aldehyde content in flavored electronic cigarette liquids. The study aims to quantify the levels of sugars (glucose, sucrose, and fructose) and aldehydes (formaldehyde, acetaldehyde, acrolein, and vanillin) in flavored unheated e-cigarette liquids and examines product labeling of these constituents in e-cigarette liquids. The data can inform the regulation of specific flavor constituents in tobacco products as a strategy to protect young people from using e-cigarettes.

Key points:

* The study analyzed 66 e-cigarette liquid bottles from seven different vendors.
* The samples were selected based on the top brands and flavors sold within the store.
* Four different nicotine concentrations were selected for each flavor.
* The samples were analyzed using liquid chromatography mass spectrometry (LCMS) and enzymatic test kits.
* Sugars and aldehydes were identified in unheated e-cigarette liquids, and their composition may influence experimentation in naïve users and their potential toxicity.
* There were no significant differences in sugar and aldehyde levels between nicotine-based and zero-nicotine labeled e-cigarette liquids.
* The study found significant correlations between formaldehyde and fructose and sucrose, as well as acrolein and fructose and sucrose.
* The data can be used to educate consumers about ingredients in products that may contain nicotine and inform future FDa regulatory policies related to product standards and accurate and comprehensible labeling of e-cigarette liquids.

Main message:
The study highlights the importance of regulating specific flavor constituents in tobacco products as a strategy to protect young people from using e-cigarettes. The data can inform regulatory policies related to product standards and accurate and comprehensible labeling of e-cigarette liquids. The study also emphasizes the potential toxicity of unheated e-cigarette liquids, even in the absence of nicotine. Therefore, it is crucial to regulate e-cigarette liquids' sugar and aldehyde content to ensure the safety of consumers.

Fagan, Pebbles, Pallav Pokhrel, Thaddeus a herzog, Eric T Moolchan, Kevin D Cassel, adrian a Franke, Xingnan Li, et al. “Sugar and aldehyde Content in Flavored Electronic Cigarette Liquids.” Nicotine & Tobacco Research 20, no. 8 (July 9, 2018): 985–92. https://doi.org/10.1093/ntr/ntx234.