Summary
The findings from various clinical laboratory studies suggest that Electronic Cigarette (ECIG) acute effects are influenced by factors such as device features, liquid constituents, and user puffing behavior. When assessing ECIGs, many study protocols consider two or more puffs separated by less than 100 ms into a single puff and exclude any puffs less than 300 ms. Statistical analyses have been conducted using IBM SPSS (Version 24.0), and repeated measures analysis of variance (aNOVas) were used to examine plasma nicotine, heart rate, puff topography, subjective effects, and total amount of liquid consumed.
These studies reveal that ECIG users' puffing behavior may vary based on the device and liquid used. For instance, users may take more intensive puffs when switching from "full-flavor" to "low-yield" ECIGs, which may lead to similar nicotine exposure and puff topography as "full-flavor" cigarettes. Consequently, switching to "low-yield" ECIGs might not significantly reduce smoking-related harm, as demonstrated in a study where smokers who switched to "low-yield" cigarettes still had expired air CO levels consistent with smoking "full-flavor" cigarettes.
In summary, the findings underline the importance of considering various factors, such as device features, liquid constituents, and user puffing behavior, when evaluating ECIG acute effects. The results suggest that switching to "low-yield" ECIGs might not effectively reduce smoking-related harm due to potential changes in puffing behavior and subsequent toxicant exposure.
Citation
hiler MM. The Influence of Electronic Cigarette heating Coil Resistance on Nicotine Delivery, heart Rate, Subjective Effects, and Puff Topography. Ph.D. Virginia Commonwealth University; 2019.
