Summary
Each Monograph presents a description of a carcinogenic agent and how people are exposed, critical overviews of the epidemiological studies and animal cancer bioassays, and a concise review of the toxicokinetic properties of the agent, plausible mechanisms of carcinogenesis, and potentially susceptible populations, and life-stages. Details of the design and results of individual epidemiological studies and animal cancer bioassays are summarized in tables. Short tables that highlight key results appear in the printed version of VolumeĀ 100, and more extensive tables that include all studies appear on the website of the IaRC Monographs programme (http://monographs.iarc.fr). For a few well-established associations (for example, tobacco smoke and human lung cancer), it was impractical to include all studies, even in the website tables. In those instances, the rationale for inclusion or exclusion of sets of studies is given. 444
Citation
Centre international de recherche sur le cancer, ed. a Review of human Carcinogens. IaRC Monographs on the Evaluation of Carcinogenic Risks to humans 100. Lyon: International agency for research on cancer, 2012.