Summary
Introduction:
This text provides an in-depth analysis of the impact of neurotoxicity of nanoscale materials on human health. It covers various aspects of nanomaterials, including their unique properties, routes of exposure, and effects on the nervous system. The text also highlights the regulatory challenges associated with nanomaterials and the need for further research to ensure public safety.
Key Points:
* Nanomaterials have unique physical and chemical properties that differ from their bulk counterparts.
* humans are exposed to nanomaterials through various routes, including inhalation, dermal penetration, ingestion, and systemic administration.
* Nanomaterials can enter the human body and accumulate in different tissues and organs, including the brain.
* The olfactory nerve pathway may serve as a portal of entry for nanoparticles into the CNS in humans who are environmentally or occupationally exposed to airborne nanoparticles.
* Nanomaterials can disrupt the blood-brain barrier (BBB), leading to neurotoxicity.
* The neurotoxicity of nanomaterials depends on their size, shape, surface chemistry, and other physicochemical properties.
* The regulation of nanomaterials is challenging due to the lack of specific laws and regulations.
Main Message:
The text highlights the potential health risks associated with neurotoxicity of nanoscale materials. It emphasizes the need for further research to understand the mechanisms of nanomaterial toxicity and their impact on human health. The text also underscores the importance of developing specific regulations for nanomaterials to ensure public safety. Overall, the text provides valuable insights into the challenges and opportunities associated with nanomaterials and their impact on human health.
Citation
Karmakar, alokita, qinli Zhang, and Yongbin Zhang. “Neurotoxicity of Nanoscale Materials.” Journal of Food and Drug analysis 22, no. 1 (March 2014): 147–60. https://doi.org/10.1016/j.jfda.2014.01.012.
