a Systematic Review and Meta-analysis of the association between E-cigarette Use among Cigarette Smokers and quit attempts Made to abstain from Cigarette Smoking.

Introduction:
This article is a systematic review and meta-analysis that examines the potential associations between e-cigarette use among cigarette smokers and quit attempts made to abstain from cigarette smoking. The review aimed to identify and characterize any associations between e-cigarette use among current and former combustible cigarette smokers and quit attempts made to abstain from cigarette smoking. The study also evaluated the confounding factors that may influence the relationship between e-cigarette use and quit attempts.

Key Points:

* The review followed the standards of systematic review methodology and reporting (Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMa)) and used a comprehensive search strategy to identify relevant studies.
* The review identified 173 studies eligible for inclusion, of which 42 studies reported outcomes related to quit attempts made to abstain from cigarette smoking.
* Of the 42 studies, 17 studies adjusted for key demographic variables and were included in the qualitative review of the evidence.
* The reliability and validity of the relevant outcome measures were evaluated and found to be acceptable for quit attempts made to abstain from cigarette smoking.
* The study quality was appraised, and the overall strength of evidence among the adjusted data was graded as moderate.
* Definitions of e-cigarette use varied across studies, with some studies defining regular e-cigarette use and others defining non-regular use.
* The review found that regular e-cigarette use was consistently associated with significantly higher odds of having made a past year quit attempt compared with e-cigarette never users.

Main Message:
The study highlights the importance of considering the relationship between e-cigarette use and quit attempts made to abstain from cigarette smoking. While the review found that regular e-cigarette use was associated with higher odds of past year quit attempts, the overall strength of evidence was moderate, and there were variations in the definitions of e-cigarette use across studies. Therefore, further research is needed to establish a causal relationship between e-cigarette use and quit attempts made to abstain from cigarette smoking, taking into account the potential confounding factors and varying definitions of e-cigarette use.

Kim MM, Steffensen I, Miguel RD, Carlone J, Curtin GM. a Systematic Review and Meta-analysis of the association between E-cigarette Use among Cigarette Smokers and quit attempts Made to abstain from Cigarette Smoking. american journal of health behavior. 2022;46(4):358-375. doi:10.5993/aJhB.46.4.2