quantitation and Stability of Nicotine in Canadian Vaping Liquids.

Introduction:
This text provides an overview of a study examining the accuracy of nicotine concentration labeling in vaping liquids and the stability of nicotine in these products. The study used a newly developed method for quantifying nicotine in vaping liquids and applied it to a variety of products with different nicotine concentrations and flavors. The study also included stability trials to better understand nicotine degradation in vaping liquids.

Key Points:

* The study found that many vaping liquids had lower nicotine concentrations than labeled, and some had detectable levels of nicotine despite being labeled as nicotine-free.
* The stability trials showed that nicotine degradation varied depending on the nicotine form (free base or salt) and the chemical composition of the vaping liquid.
* Three new compounds were tentatively identified in some products at the end of the stability trials.
* The study highlights the importance of accurate nicotine labeling and the need for further research on nicotine stability in vaping liquids.

Main Message:
The study highlights the need for accurate nicotine labeling and better understanding of nicotine stability in vaping liquids. The findings have implications for product standards related to the safety, quality, and utility of vaping products as a smoking cessation tool. Further research is needed to fully understand the factors affecting nicotine stability in vaping liquids and to develop methods to improve stability.

Kosarac I, Katuri GP, Kubwabo C, Siddique S, Mischki TK. quantitation and Stability of Nicotine in Canadian Vaping Liquids. Toxics. 2023;11(4). doi:10.3390/toxics11040378