Summary
Introduction:
This text summarizes the findings of a study analyzing the relationship between e-cigarette use, conventional cigarette smoking, and high-sensitivity C-reactive protein (hs-CRP), a marker of inflammation and a predictor of cardiovascular disease (CVD). The study utilizes data from the National health and Nutrition Examination Survey (NhaNES) 2015-2016, and adjusts for various factors such as age, sex, race/ethnicity, obesity, and previous diagnosis of diabetes.
Key Points:
* The study included 4,659 participants, with 33.7% having elevated hs-CRP levels.
* Prevalence of high-risk CRP was highest among dual users (45.6%) and lowest among current e-cigarette users (28.9%).
* Dual users had the highest serum cotinine levels (mean level at 220.9 ng/ml).
* Compared with nonsmokers, cigarette only smokers and dual users were 1.3 to 2.1 times more likely to have elevated hs-CRP.
* There was no significant difference between nonsmokers and e-cigarette only users in the likelihood of having elevated hs-CRP.
* The study has limitations, including lack of data on e-cigarette brand, flavoring, and intensity of use.
* The authors report no relevant relationships to disclose.
Main Message:
The study's main message is that conventional cigarette smoking and dual use of e-cigarettes and conventional cigarettes are associated with a higher likelihood of having an elevated CRP level, which is a predictor of cardiovascular disease. The findings suggest that continued use of both conventional and e-cigarettes may not be advisable. additionally, the study highlights the need to consider the potential for sustained dual use when evaluating the impact of e-cigarettes on cardiovascular health.
Citation
Mainous aG, Yadav S, hong YR, huo J. e-Cigarette and Conventional Tobacco Cigarette Use, Dual Use, and C-Reactive Protein. Journal of the american College of Cardiology. 2020;75(17):2271-2273. doi:10.1016/j.jacc.2020.02.061
