Summary
Introduction:
This text describes a scientific study that investigated the effects of electronic cigarette (e-cigarette) vaping on the cytoarchitecture of the tongue in adult male albino rats. The study also assessed the potential amelioration of these changes after the rats stopped vaping.
Key Points:
* The study exposed rats to e-cigarette vapor for 1 hour, 5 days a week, for 4 weeks.
* The study found that e-cigarette vaping led to histopathological changes in the tongue, including loss of some papillae and hyperkeratosis of others.
* The study also found that e-cigarette vaping increased proliferating cell nuclear antigen (PCNa) immunoreactivity and its area percentage in the tongue.
* additionally, e-cigarette vaping resulted in redox imbalance, as evidenced by increased malondialdehyde (MDa) and decreased superoxide dismutase (SOD) activity.
* after the rats stopped vaping for another 4 weeks, the study found partial amelioration of the histological and biochemical changes.
* The study concludes that e-cigarette vaping produced proliferative changes that impose a metaplasia in the tongue, and their withdrawal revealed some degree of improvement.
Main Message:
This study suggests that e-cigarette vaping has detrimental effects on the cytoarchitecture of the tongue, leading to proliferative changes and redox imbalance. The study also indicates that stopping e-cigarette vaping may result in some improvement in these changes. Therefore, it is crucial to regulate e-cigarette use and inform the public about its potential health risks.
Citation
Mandour Da, Saber SM, Soliman RhM, abdelfattah MT. Impact of electronic cigarette vaping on the cytoarchitecture of the tongue in the adult male albino rat. Zagazig Univ Med J. 2022;28:1346-1354. doi:10.21608/zumj.2021.88065.2301
