Summary
Introduction:
This text reports a study that aimed to develop a method for determining menthol in a single puff of mainstream cigarette smoke. The study used a rotary smoking machine with a twin filter interface to smoke cigarettes with varying menthol and tar deliveries and collected smoke from each puff on separate filter pads for analysis. The individual filter pad extracts were then analyzed by gas chromatography-mass spectrometry (GC-MS) to determine menthol puff-by-puff deliveries.
Key Points:
* The study used a rotary smoking machine with a twin filter interface to smoke cigarettes and collect smoke from each puff on separate filter pads.
* The individual filter pad extracts were analyzed by GC-MS to determine menthol puff-by-puff deliveries.
* Menthol puff-by-puff profiles show an increase in menthol smoke delivery within increasing puff count.
* The sum of single puff menthol deliveries is comparable to the whole cigarette menthol smoke delivery as collected on a single filter pad.
* This method can also determine quantitative puff-by-puff deliveries of other mainstream smoke constituents.
* The study used commercially available menthol cigarettes with increasing tar and menthol deliveries.
* The cigarettes were smoked following the Cambridge filter method with a 35 mL puff volume, 2 second puff duration, and 60 second puff interval.
Main Message:
The study reports a method for determining menthol in a single puff of mainstream cigarette smoke using a rotary smoking machine with a twin filter interface and GC-MS analysis. The study found that menthol puff-by-puff deliveries increase with increasing puff count and the sum of single puff menthol deliveries is comparable to the whole cigarette menthol smoke delivery. This method can also be used to determine quantitative puff-by-puff deliveries of other mainstream smoke constituents. The study highlights the importance of developing accurate and reliable methods for determining the composition of cigarette smoke and the potential implications for regulatory matters.
Citation
Meruva, Nk, Mt Smith, and Se Plunkett. “quantitative Determination of Menthol in a Single Puff of Mainstream Cigarette Smoke.” Beiträge Zur Tabakforschung International/Contributions to Tobacco Research 25, no. 5 (March 1, 2013): 528–34. https://doi.org/10.2478/cttr-2013-0928.
