Summary
probabilistic risk assessment study of chemical constituents in mainstream smoke of cigarettes sold in China, conducted by Xie et al. in 2012, published in the journal Regulatory Toxicology and Pharmacology. The study aimed to prioritize chemical constituents based on their potential harm to human health.
The study used a probabilistic risk assessment approach, which involves estimating the probability of an adverse effect occurring due to exposure to a particular chemical. This approach takes into account variability in exposure levels, toxicity of the chemical, and other factors that can affect the risk.
The findings of the study suggest that certain chemical constituents in cigarette smoke, such as polycyclic aromatic hydrocarbons (Pahs) and tobacco-specific nitrosamines (TSNas), pose a higher risk to human health than others. The study also highlights the importance of considering the toxicity of each chemical individually, rather than simply looking at the overall smoke composition.
The document also references a standard operating procedure (SOP 01) for intense smoking of cigarettes, developed by the World health Organization (WhO), which provides a method for testing cigarettes under standardized conditions to ensure consistent and reliable results.
additionally, the document cites a report by the WhO Study Group on Tobacco Product Regulation, which provides a scientific basis for tobacco product regulations and highlights the importance of regulating tobacco products to reduce their harm to human health.
In summary, the study by Xie et al. provides a probabilistic risk assessment of chemical constituents in cigarette smoke sold in China, highlighting the higher risk posed by certain chemicals. The document also references standardized testing methods and scientific reports that support tobacco product regulations to reduce their harm to human health.
Citation
Phillip Morris Products. "aerosol Chemistry." (2017)
