Vaping-associated Lung Injury: a Review.

Introduction:
This text provides an in-depth analysis of the impact of e-cigarettes on population health, focusing on the potential toxicity and lung injury associated with their use. The reader will learn about the chemical composition of e-cigarettes, the short and long-term health effects, and the regulatory landscape surrounding their use.

Key Points:

* E-cigarettes contain various chemicals, such as nicotine, flavourings, and vegetable glycerin or propylene glycol.
* Exposure to e-cigarettes can lead to toxicity, primarily due to oxidative stress and endothelial cell dysfunction.
* Vaping has been associated with increased cough, wheeze, and asthma exacerbations in adolescents.
* a link between e-cigarette use and lung injury has been reported, with ThC-containing products being a significant contributor.
* Vitamin E acetate, a thickening agent in e-liquids, has been identified as a potential cause of lung injury.
* The FDa has extended its Premarket Tobacco Product application to e-cigarettes and vaping products, ensuring standardization and regulation.
* The high prevalence of youth and young adult use of nicotine and cannabis e-cigarettes remains a concern.

Main Message:
The text emphasizes the need for further research on the health effects of e-cigarettes, particularly in relation to lung injury and toxicity. additionally, it highlights the importance of regulatory measures to ensure the safety and standardization of e-cigarette and vaping products. The increasing use of e-cigarettes among adolescents, particularly for cannabis vaping, poses a significant public health concern and warrants attention from policymakers and healthcare professionals.

O’Callaghan M, Boyle N, Fabre a, Keane MP, McCarthy C. Vaping-associated Lung Injury: a Review. Medicina (Kaunas, Lithuania). 2022;58(3). doi:10.3390/medicina58030412