Summary
Introduction: This study aimed to understand the mechanisms that underlie the use of e-cigarettes and their potential utility for smoking cessation by considering both pharmacologic and non-pharmacologic factors. The study focused on the role of sensorimotor stimuli in reducing cravings to smoke and vape.
Key Points:
* The study used a 2x2 design, crossing nicotine content (nicotine or no nicotine) with delivery apparatus (normal or altered sensorimotor) for a total of 4 conditions.
* Participants were daily cigarette smokers and e-cigarette users who were already familiar with e-cigarettes.
* The altered sensorimotor apparatus was designed to disrupt normal sensorimotor feedback, including the activation button, visibility, and hand-to-mouth movements.
* The study measured cravings to smoke and vape, as well as secondary outcomes such as positive and negative affect, appetite, and subjective reward.
* The study found that nicotine delivery had moderate effects on reducing cravings to smoke and vape, as well as increasing psychological reward.
* however, the altered sensorimotor apparatus led to greater craving reduction, contrary to the hypothesis.
* There were no significant differences in secondary outcomes based on sensorimotor manipulation.
Main Message: The study suggests that both nicotine delivery and nonpharmacological factors, such as sensorimotor stimuli, are important for reducing cravings and may be important for motivating e-cigarette use and aiding smoking cessation. however, the effects of sensorimotor stimuli may differ based on user experience and familiarity with e-cigarettes. The study highlights the need for further research to understand the mechanisms underlying the maintenance of vaping and the potential utility of e-cigarettes for smoking cessation.
Citation
Palmer aM, Sawyer LE, Brandon Th. Distinct influences of nicotine and sensorimotor stimuli on reducing cravings to smoke and vape among dual users. addictive behaviors. 2021;122:107051. doi:10.1016/j.addbeh.2021.107051
