Risk of Stroke With E-Cigarette and Combustible Cigarette Use in Young adults.

Introduction: This text summarizes a research study examining the association between e-cigarette use and stroke in young adults, while also considering the impact of combustible cigarette use. The study uses data from the Behavior Risk Factor Surveillance System to investigate the prevalence of e-cigarette and combustible cigarette use among young adults aged 18-44. The study also adjusts for various demographic factors, health conditions, and e-cigarette usage frequency.

Key Points:

* The study found that current dual use of e-cigarettes and combustible cigarettes was associated with 2.91 times higher odds of stroke compared to nonsmokers.
* Current sole e-cigarette use was not associated with greater odds of stroke compared to nonsmokers, but odds were lower compared to current sole combustible cigarette use.
* The odds of stroke were nearly 3 times higher in current dual users versus nonsmokers, even after adjusting for hypertension and cholesterol.
* Greater intensity of e-cigarette use was associated with higher stroke odds.
* There was no significant difference in stroke odds between current sole combustible cigarette use and current e-cigarette use among former combustible cigarette users.
* Consistent with prior reports, dual use demonstrated nearly 3 to 4 times amplified risk of stroke compared to nonsmokers.
* Long-term exposure to higher nicotine levels, mainly from particulate matter, increases the risk of atherosclerosis, a known risk factor of stroke.

Main Message: The study emphasizes the importance of understanding the immediate cerebrovascular effects of e-cigarette use and the potential additive cerebrovascular effects of e-cigarette ingredients. It also highlights the need for further research on the long-term health consequences of e-cigarette use, particularly in relation to nicotine concentration and stroke risk. additionally, the study underscores the need for effective tobacco product regulation and comprehensive tobacco control and prevention strategies.

Parekh T, Pemmasani S, Desai R. Risk of Stroke With E-Cigarette and Combustible Cigarette Use in Young adults. american journal of preventive medicine. 2020;58(3):446-452. doi:10.1016/j.amepre.2019.10.008