a Procedure to Standardize Puff Topography During Evaluations of acute Tobacco or Electronic Cigarette Exposure.

Introduction:
This text summarizes a scientific study investigating the effect of a simplified instructional procedure on the consistency of puff volume during smoking and vaping sessions. The study aims to evaluate the reliability of the instructional procedure across different products, nicotine levels, and subgroups of smokers. The researchers used the Clinical Research Support System (CReSS) to objectively assess puff volume, duration, number, and interpuff interval. The study includes two main parts: one examining the consistency of topography with tobacco cigarettes and another with electronic cigarettes.

Key points:

* The study used within-subject designs, with participants smoking or vaping under different manipulations.
* The CReSS was used to objectively assess puff volume, duration, number, and interpuff interval.
* The instructional procedure improved control over topography in smoking and vaping sessions.
* There were no significant differences in puff volume, duration, number, or interpuff interval between nicotine and non-nicotine cigarettes.
* Men and women, as well as menthol and non-menthol smokers, did not differ significantly in their puff volume consistency.
* The study found that the instructional procedure can be used to improve control over exposure during acute assessments of inhaled nicotine products.
* The procedure has the potential to aid validity in research on differential sensitivity to use and to isolate causal factors in differential responding.

Main message:
The study demonstrates that the instructional procedure significantly improves control over puff volume during smoking and vaping sessions. The procedure can be used to improve control over exposure during acute assessments of inhaled nicotine products and aid validity in research on differential sensitivity to use. The study highlights the potential of this simple instructional procedure as a valuable tool in research and regulation of nicotine products.

Perkins Ka, Karelitz JL. a Procedure to Standardize Puff Topography During Evaluations of acute Tobacco or Electronic Cigarette Exposure. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. 2020;22(5):689-698. doi:10.1093/ntr/nty261