Changes in Dependence as Smokers Switch from Cigarettes to JUUL in Two Nicotine Concentrations.

Introduction:
This article discusses a study on the changes in nicotine dependence among smokers who switched to JUUL, an electronic nicotine delivery system (ENDS), in two nicotine concentrations. The study aimed to assess the changes in dependence and the impact of nicotine concentration on dependence. The reader will learn about the study design, major findings, and the implications of the results.

Key Points:

* The study enrolled 5246 adult established smokers who purchased a JUUL device and completed online surveys at baseline, one month, and three months after the purchase.
* The study found that switching from smoking to exclusive use of JUUL decreased nicotine dependence, and the changes did not significantly differ between users of 5.0% and 3.0% nicotine concentrations.
* Dependence on JUUL did not change significantly from one month to three months.
* Smokers who switched to JUUL may reduce their nicotine dependence.
* The study used validated measures of nicotine dependence for assessing ENDS dependence and comparing it to cigarette dependence.
* The study found that dependence on ENDS is lower than dependence on cigarettes, including among dual users.
* The study also found that exclusive users of ENDS demonstrate higher dependence on ENDS than do dual users.
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Main Message:
The study provides valuable insights into the changes in nicotine dependence among smokers who switch to JUUL. The results suggest that switching to JUUL can decrease nicotine dependence, and the nicotine concentration does not significantly impact the level of dependence. The study's findings support the potential of ENDS as a harm reduction strategy for smokers, but further research is needed to understand the long-term effects of ENDS use. The study's use of validated measures of nicotine dependence adds to the credibility of the findings, and the results can inform regulatory decisions regarding ENDS.

Shiffman S, Goldenson NI, hatcher C, augustson EM. Changes in Dependence as Smokers Switch from Cigarettes to JUUL in Two Nicotine Concentrations. american journal of health behavior. 2021;45(3):563-575. doi:10.5993/aJhB.45.3.10