The Effects of E-Cigarette Vapor Components on the Morphology and Function of the Male and Female Reproductive Systems: a Systematic Review.

Introduction:
This text provides an in-depth analysis of the effects of e-cigarette vapor components on the morphology and function of male and female reproductive systems. It highlights recent studies that have explored this topic and summarizes their key findings. The text aims to provide readers with a comprehensive understanding of the potential risks associated with e-cigarette use and its impact on reproductive health.

Key Points:

* E-cigarettes contain harmful substances, including endocrine disruptors, that can affect hormonal balance and the morphology and function of reproductive organs.
* Exposure to e-cigarette vapor can affect fertility in both males and females.
* In male rats, exposure to e-cigarette refill liquids, with or without nicotine, can lead to oxidative stress, histopathological changes in testis morphology, and decreased circulating testosterone levels.
* Exposure to e-cigarette vapor can also affect sperm count, viability, and morphology in male rats.
* In female mice, exposure to e-cigarette vapor can delay implantation and cause reduced weight gain in female offspring exposed in utero.
* The impact of e-cigarette exposure on human reproductive organs is not yet fully understood, but the data from animal models is concerning.
* E-cigarettes, even when nicotine-free, cannot be considered completely safe and may have negative effects on reproductive health.

Main Message:
The text highlights the potential risks associated with e-cigarette use and its impact on reproductive health. While more research is needed to fully understand the effects of e-cigarette vapor components on human reproductive organs, the data from animal models suggests that e-cigarettes may not be a completely safe alternative to smoking. E-cigarettes, even when nicotine-free, contain harmful substances that can affect hormonal balance and the morphology and function of reproductive organs. Therefore, it is crucial to regulate the use and composition of e-cigarettes to minimize potential health risks.

Szumilas K, Szumilas P, Grzywacz a, Wilk a. The Effects of E-Cigarette Vapor Components on the Morphology and Function of the Male and Female Reproductive Systems: a Systematic Review. International journal of environmental research and public health. 2020;17(17). doi:10.3390/ijerph17176152