a comparison of the electrical characteristics, liquid composition, and toxicant emissions of JUUL USa and JUUL UK e-cigarettes.

Introduction:
This text is a scientific report on a study comparing the electrical characteristics, liquid composition, and toxicant emissions of JUUL e-cigarettes sold in the USa and the UK. The study aimed to determine if JUUL Labs modified the device design to comply with EU regulations limiting liquid nicotine concentration. The report highlights the differences and similarities between the two versions of JUUL e-cigarettes and their implications for public health.

Key Points:

* JUUL Labs did not re-engineer the device or liquid apart from reducing nicotine concentration to comply with EU restrictions on nicotine content.
* JUUL UK has approximately one-third the nicotine concentration and yield compared to JUUL USa.
* Both versions emit similar levels of carbonyl compounds, but JUUL UK exhibits approximately double the methylglyoxal as JUUL USa.
* ROS emissions are not significantly different across devices, but JUUL UK's toxicant emissions are approximately three times those of JUUL USa, per unit nicotine emitted.
* JUUL devices sold in the UK and USa are generally the same, except for nicotine liquid concentration and yield.
* Users of JUUL UK devices may adjust their puffing patterns to obtain similar levels of nicotine as obtained with the JUUL USa devices.
* The study highlights an ongoing natural experiment on the manipulation of nicotine content in the world's most popular electronic cigarette product.

Main Message:
The study highlights the importance of monitoring and regulating nicotine content in electronic cigarettes to reduce toxicant exposure and health risks. The findings suggest that reducing nicotine concentration in e-cigarettes may result in users adjusting their puffing patterns to obtain similar levels of nicotine, leading to higher measured carbonyl emissions. Therefore, further research is necessary to understand the population characteristics, toxicant exposure, pod consumption, and reported health effects associated with regulating nicotine concentration in e-cigarettes.

Talih S, Salman R, El-hage R, et al. a comparison of the electrical characteristics, liquid composition, and toxicant emissions of JUUL USa and JUUL UK e-cigarettes. Scientific reports. 2020;10(1):7322. doi:10.1038/s41598-020-64414-5