Summary
Introduction:
This text is a summary of a scientific study investigating the acute effects of exposure to propylene glycol (PG) mist on the respiratory and ocular health of non-asthmatic volunteers. The study was conducted in an aircraft simulator during realistic training conditions.
Key Points:
* The study found that short exposure to PG mist from artificial smoke generators may cause acute ocular and upper airway irritation in non-asthmatic subjects.
* a few participants also experienced cough and slight airway obstruction.
* The concentration of PG mist in the aircraft simulator was higher than in other occupational exposures to this compound.
* The study used a standardized method to estimate tear film stability, acoustic rhinometry to measure nasal patency, and dynamic spirometry to assess lung function.
* The study found that tear film stability decreased, ocular and throat symptoms increased, and there was a slight reduction in FEV1/FVC after exposure to PG mist.
* No effects were found on nasal patency, vital capacity, or systemic symptoms.
* Those exposed to higher concentrations of PG mist had a more pronounced increase in throat symptoms and a more pronounced decrease in tear film stability.
Main Message:
The main message of this study is that exposure to high concentrations of PG mist from artificial smoke generators may cause ocular and respiratory irritation in non-asthmatic subjects, and sensitive individuals should be protected or avoid extreme or prolonged exposure. The study highlights the importance of monitoring and controlling exposure to PG mist in workplaces and public places.
Citation
Wieslander, G, D Norbäck, and T Lindgren. “Experimental Exposure to Propylene Glycol Mist in aviation Emergency Training: acute Ocular and Respiratory eVects,” 2001.
