Initial puffing behaviors and subjective responses differ between an electronic nicotine delivery system and traditional cigarettes

Introduction:
This text provides an analysis of a study that compares the initial puffing behaviors and subjective responses of an electronic nicotine delivery system (ENDS) and traditional cigarettes. The study measures exhaled carbon monoxide (CO) and salivary cotinine concentration, cigarette craving after a 72-hour abstinence, and subjective product effects. The study also records puff volume, duration, flow rate, and inter-puff interval.

Key Points:

* The study involved 38 participants who were asked to abstain from regular cigarettes for 72 hours and use an ENDS instead.
* The study found significant differences in puff count, average volume, total volume, and inter-puff interval between the two products, with ENDS showing a more intensive smoking pattern.
* Cigarette craving scores dropped significantly after smoking regular cigarettes, but not after using ENDS.
* ENDS were rated less favorably than regular cigarettes in subjective measures.
* CO boost, after ENDS use, decreased significantly, and saliva cotinine significantly dropped between visits 1 and 3 after ENDS use relative to after cigarette smoking.
* Compliant and non-compliant participants showed an average 82.0% and 73.9% reduction in regular cigarette use per day during the ENDS trial period, respectively.
* The study has implications for the viability of certain ENDS as alternatives to cigarettes.

Main Message:
The main message of this study is that initial puffing behaviors and subjective responses differ between ENDS and traditional cigarettes. The study found that ENDS were used more intensively, but delivered significantly less nicotine and were less satisfying than regular cigarettes. These findings suggest that certain ENDS may not be a viable alternative to cigarettes, and further research is needed to assess their potential as substitutes. The study also highlights the importance of understanding consumer perception and the need for regulation to clarify the potential public health risks and benefits of ENDS.

Norton, Kaila J, Kristie M June, and Richard J O’Connor. “Initial Puffing Behaviors and Subjective Responses Differ between an Electronic Nicotine Delivery System and Traditional Cigarettes.” Tobacco Induced Diseases 12, no. 1 (2014): 17. https://doi.org/10.1186/1617-9625-12-17.