Toxicity assessment of flavour chemicals used in e-cigarettes: current state and future challenges.

This text discusses the potential health risks associated with the inhalation of flavoring chemicals used in e-cigarettes. although these flavorings are generally recognized as safe for oral use, their safety for inhalation is not assured. The text highlights the need for comprehensive safety evaluations of these flavorings and combinations thereof, including toxicological endpoints such as genotoxicity/carcinogenicity, inhalation toxicity, and respiratory sensitization. additionally, the text emphasizes the need for additional information on realistic exposure scenarios for different e-cigarette devices to better regulate these compounds and, if necessary, restrict their use by setting limit values.

Barhdadi S, Rogiers V, Deconinck E, Vanhaecke T. Toxicity assessment of flavour chemicals used in e-cigarettes: current state and future challenges. archives of toxicology. 2021;95(8):2879-2881. doi:10.1007/s00204-021-03080-6