Characterization of Ad Libitum Use Behavior of On! Nicotine Pouches

Introduction:
This text provides a summary of a study examining the use behavior of nicotine pouches, specifically the on!® nicotine pouches, over an extended duration and their interaction with cigarette and smokeless tobacco product use. The study's design, key points, and main message are summarized below.

Key Points:

* The study enrolled adults who smoke cigarettes, adults who use smokeless tobacco products, and adults who smoke cigarettes and use smokeless tobacco products.
* Participants were offered ad libitum use of on!® nicotine pouches for six weeks and asked to report their tobacco product use daily.
* The median number of pouches consumed was about 5-6 per day, and use behavior was relatively consistent across flavors and nicotine levels.
* By Week 6, 27% of adults who smoke cigarettes and 71% of adults who use smokeless tobacco products reported no use of cigarettes or smokeless tobacco products, respectively.
* A statistically significant inverse relationship was found between TP flavor varieties and number of cigarettes or smokeless tobacco use occasions.
* The study suggests that on!® nicotine pouches can serve as a substitute for cigarettes or smokeless tobacco products and may offer harm reduction potential for adults not interested in quitting.

Main Message:
The study suggests that on!® nicotine pouches can be potential substitutes for cigarettes and smokeless tobacco products, and complete switching may offer harm reduction potential for adults who smoke cigarettes or use smokeless tobacco products not interested in quitting. The availability of a variety of flavors and nicotine levels may facilitate adoption and switching from cigarettes or smokeless tobacco products. However, further research is needed to confirm these findings and assess long-term health effects.

Becker, E., McCaffrey, S., Lewis, J., Vansickel, A., Larson, E., & Sarkar, M. (2023). Characterization of Ad Libitum Use Behavior of On! Nicotine Pouches. American Journal of Health Behavior, 47(3), 428–449. https://doi.org/10.5993/AJHB.47.3.1