a case of nicotine fatality due to oral ingestion of e-cigarette liquid was reported in the Journal of Forensic Sciences in 2016. The study determined the levels of nicotine, cotinine, and trans-3'-hydroxycotinine in the blood and vitreous humor of the deceased using LC/MS/MS. In 2014, Zhu et al. identified 460 brands of e-cigarettes, highlighting the challenges in regulating these products. a study published in the american Journal of Preventive Medicine in 2017 reported an increase in the prevalence of e-cigarette use among adults in the US.
Wu et al. found that electronic cigarette liquid increased inflammation and virus infection in primary human airway epithelial cells in a 2014 study published in PLoS One.
These findings suggest that e-cigarettes and their liquid contents pose potential health risks, including nicotine poisoning, increased inflammation, and virus infection. The variety of e-cigarette brands available further complicates the regulation of these products.
Citation
Chun, Lauren F., Farzad Moazed, Carolyn S. Calfee, Michael a. Matthay, and Jeffrey E. Gotts. “Pulmonary Toxicity of E-Cigarettes.” american Journal of Physiology-Lung Cellular and Molecular Physiology 313, no. 2 (august 1, 2017): L193–206. https://doi.org/10.1152/ajplung.00071.2017.
Chun, Lauren F., Farzad Moazed, Carolyn S. Calfee, Michael a. Matthay, and Jeffrey E. Gotts. “Pulmonary Toxicity of E-Cigarettes.” american Journal of Physiology-Lung Cellular and Molecular Physiology 313, no. 2 (august 1, 2017): L193–206. https://doi.org/10.1152/ajplung.00071.2017.
