Combinations of electronic nicotine delivery system device and liquid characteristics among U.S. adults.

Introduction:
This text provides a comprehensive analysis of the use of electronic nicotine delivery systems (ENDS) among U.S. adults, with a focus on the combinations of device and liquid characteristics. The study examines the most common pairings of device and liquid features and their association with nicotine and toxicant exposure. The findings have implications for the regulation of ENDS devices and liquids.

Key Points:

* The study is based on an online survey of U.S. adults who use ENDS at least five days per week and uploaded photos of their most used device and liquid.
* Five device/liquid combinations accounted for 87% of those reported.
* The most prevalent combination, reported by 36.2%, was re-useable devices with adjustable settings and a tank refilled with a free-base nicotine liquid with a median nicotine concentration of 5.2 mg/mL.
* Wattage, voltage and resistance varied across device/liquid combination.
* Overall, 66.5% refilled their device’s tank or pod and 64.2% had the ability to manipulate device characteristics (power, airflow, and/or coil).
* The findings highlight the need for regulations that consider the combination of device and liquid characteristics, rather than each separately.
* additional research is needed to determine whether certain combinations are more effective at helping smokers quit and which device/liquid combinations should remain on the market.

Main Message:
The study underscores the importance of considering the combination of device and liquid characteristics when regulating ENDS devices and liquids. The findings highlight the need for regulations that take into account the diversity of device and liquid combinations and their impact on nicotine and toxicant exposure. The results also suggest that further research is needed to determine the most effective combinations for helping smokers quit and to inform regulatory decisions. Overall, the text emphasizes the need for a comprehensive and evidence-based approach to the regulation of ENDS devices and liquids.

Cohen JE, hardesty JJ, Nian q, et al. Combinations of electronic nicotine delivery system device and liquid characteristics among U.S. adults. addictive behaviors. 2022;135:107441. doi:10.1016/j.addbeh.2022.107441