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A 90-Day Subchronic Exposure to Heated Tobacco Product Aerosol Caused Differences in Intestinal Inflammation and Microbiome Dysregulation in Rats

Author: Tian

Year Published: 2025

Summary

Introduction:
This text provides a comprehensive summary of predictors of vaping cessation behaviors among young people. It highlights the findings of a systematic review that aimed to identify individual and environmental factors associated with intention to quit vaping, quit attempts, and vaping abstinence. The review included 24 studies and categorized the predictors into five groups: "probable," "possible," "insufficient evidence," "probably unrelated," and "inconsistent direction."

Key Points:

* The review identified a wide variety of factors that predict vaping cessation behaviors among young people.
* Most of the studies examined predictors of intention to quit vaping and quit attempts, while only one-third of the studies focused on vaping abstinence or quit success.
* The "probable" predictors of vaping cessation behaviors include demographics, reasons for using e-cigarettes, e-cigarette use pattern-related factors, harm perception of vaping, level of nicotine dependence, peer/family-related factors, OTPs and other substance use-related factors, and exposure to anti-vaping contents.
* The review found that having high harm perception of vaping increases the probability of intention to quit vaping, quit attempts, and vaping abstinence.
* Current OTPs use decreases the probabilities of intention to quit vaping and being abstinent but increases the probability of making a quit attempt.
* Younger people might have higher likelihood of successful quitting than older individuals.
* The level of nicotine dependence negatively impacts making quit attempts and vaping abstinence.
* Disposable e-cigarette device use increases the likelihood of intention to quit vaping, and using a sweet flavor in e-cigarettes lowers the likelihood of being abstinent.
* The predictors of vaping abstinence were mostly detected by longitudinal studies, while those of intention to quit and quit attempts were detected by mainly cross-sectional studies.
* More prospective longitudinal research is needed to further identify and explore all three outcomes.

Main Message:
The text highlights the importance of understanding the predictors of vaping cessation behaviors among young people. The findings of the review can guide vaping cessation approaches and inform public health policy. The review emphasizes the need for more prospective longitudinal research to further identify and explore the predictors of vaping cessation behaviors. The text also highlights the significance of raising awareness regarding the potential health risks of nicotine vaping and conducting research in different jurisdictions and population groups to better understand the factors that influence young people's vaping cessation behaviors.

Citation

Yushan Tian, Jiale Cheng, Yanan Yang, Hongjuan Wang, Yaning Fu, Xianmei Li, Wenming Wang, Shuhao Ma, Xiaoxiao Xu, Fengjun Lu, Pengxia Feng, Shulei Han, Huan Chen, Hongwei Hou, Qingyuan Hu, Chongming Wu, A 90-Day Subchronic Exposure to Heated Tobacco Product Aerosol Caused Differences in Intestinal Inflammation and Microbiome Dysregulation in Rats, Nicotine & Tobacco Research, Volume 27, Issue 3, March 2025, Pages 438–446, https://doi.org/10.1093/ntr/ntae179
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