Guidance Document on Good In Vitro Method Practices (GIVIMP)
Non-Clinical
Chemical
Methods
OECD (2018)
high-Nicotine Electronic Cigarette Products: Toxicity of JUUL Fluids and aerosols Correlates Strongly with Nicotine and Some Flavor Chemical Concentrations
Non-Clinical
Cytotoxicity
Omaiye (2019)
Evaluation of the Tobacco heating System 2.2. Part 6: 90-day OECD 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects of a mentholated version compared with mentholated and non-mentholated cigarette smoke
Non-Clinical
Safety Effects In Animals
Repeat-dose Toxicity
Oviedo (2016)
Detection and characterization of mechanisms of action of aneugenic chemicals
Non-Clinical
Chemical
Analysis
Parry (2002)
activation of the cold-receptor TRPM8 by low levels of menthol in tobacco products
Non-Clinical
Chemical
Analysis
Paschke (2017)
Concentration of Nicotine and Glycols in 27 Electronic Cigarette Formulations
Non-Clinical
Chemical
Analysis
Peace (2016)
a Systematic Reveiw of health Effects of Electronic Cigarettes
Non-Clinical
Respiratory Toxicity
Pisinger (2014)
Systems toxicology-based assessment of the candidate modified risk tobacco product ThS2.2 for the adhesion of monocytic cells to human coronary arterial endothelial cells
Non-Clinical
Cardiovascular Toxicity
In Vitro
Poussin (2016)