Electronic cigarette exposure causes vascular endothelial dysfunction due to NaDPh oxidase activation and eNOS uncoupling.
Nonclinical
Cardiovascular Toxicity
In Vivo
El-Mahdy (2022)
Nicotine and novel tobacco products drive adverse cardiac remodeling and dysfunction in preclinical studies.
Nonclinical
Cardiovascular Toxicity
In Vivo
Fried (2022)
addressing the challenges of E-cigarette safety profiling by assessment of pulmonary toxicological response in bronchial and alveolar mucosa models.
Nonclinical
Cardiovascular Toxicity
In Vitro
Ganguly (2020)
Electronic cigarettes cause alteration in cardiac structure and function in diet-induced obese mice.
Nonclinical
Cardiovascular Toxicity
In Vivo
hasan (2020)
The flavoring and not the nicotine content is a decisive factor for the effects of refill liquids of electronic cigarette on the redox status of endothelial cells.
Nonclinical
Cardiovascular Toxicity
In Vivo
Kerasioti (2020)
Short-term e-cigarette vapour exposure causes vascular oxidative stress and dysfunction: evidence for a close connection to brain damage and a key role of the phagocytic NaDPh oxidase (NOX-2).
Nonclinical
Cardiovascular Toxicity
In Vivo
Kuntic (2020)
The role of acrolein for E-cigarette vapour condensate mediated activation of NaDPh oxidase in cultured endothelial cells and macrophages.
Nonclinical
Cardiovascular Toxicity
In Vivo
Kuntic (2023)
Impact of cigarette versus electronic cigarette aerosol conditioned media on aortic endothelial cells in a microfluidic cardiovascular model.
Nonclinical
Cardiovascular Toxicity
In Vitro
Makwana (2021)
In Vitro Biological Effects of E-Cigarette on the Cardiovascular System-Pro-Inflammatory Response Enhanced by the Presence of the Cinnamon Flavor.
Nonclinical
Cardiovascular Toxicity
In Vitro
Michon (2022)
Systems toxicology-based assessment of the candidate modified risk tobacco product ThS2.2 for the adhesion of monocytic cells to human coronary arterial endothelial cells
Non-Clinical
Cardiovascular Toxicity
In Vitro
Poussin (2016)