In vitro and in silico genetic toxicity screening of flavor compounds and other ingredients in tobacco products with emphasis on ENDS.
Nonclinical
Genotoxicity
In Vitro
hung (2020)
The effects of prenatal nicotine and ThC E-cigarette exposure on motor development in rats.
Nonclinical
Reproductive & Developmental Effects
In Vivo
hussain (2022)
Inflammation and oxidative stress from E-cigarette exposure: implications for COPD and asthma.
Nonclinical
Immunotoxicity
In Vivo
hutchinson (2022)
Electronic cigarettes promotes the lung colonization of human breast cancer in NOD-SCID-Gamma mice.
Nonclinical
Carcinogenicity
In Vivo
huynh (2020)
Micronucleus tests in mice on 39 food additives and eight miscellaneous chemicals
Nonclinical
Safety Effects In Animals
hayashi (1988)
Risk analysis for the Carcinogen Pulegone in Mint- and Menthol-Flavored e-Cigarettes and Smokeless Tobacco Products.
Nonclinical
Carcinogenicity
In Vitro
Jabba (2019)
Chemical adducts of Reactive Flavor aldehydes Formed in E-Cigarette Liquids are Cytotoxic and Inhibit Mitochondrial Function in Respiratory Epithelial Cells.
Nonclinical
Cytotoxicity
In Vivo
Jabba (2020)
Synthetic Cooling agents in US-marketed E-cigarette Refill Liquids and Popular Disposable E-cigarettes: Chemical analysis and Risk assessment.
Nonclinical
Chemical
Analysis
Jabba (2022)
a lower impact of an acute exposure to electronic cigarette aerosols than to cigarette smoke in human organotypic buccal and small airway cultures was demonstrated using systems toxicology assessment.
Nonclinical
Respiratory Toxicity
In Vitro
Iskandar (2019)
an inter-laboratory in vitro assessment of cigarettes and next generation nicotine delivery products.
Nonclinical
ALL
In Vitro
Ito (2019)