Transgenic chinese hamster V79 cell lines which exhibit variable levels of gpt mutagenesis
Non-Clinical
Safety Effects In Animals
Klein and Rossman (1990)
E-cigarette or Vaping Product Use-associated Lung Injury Produced in an animal Model From Electronic Cigarette Vapor Exposure Without Tetrahydrocannabinol or Vitamin E Oil.
Nonclinical
Safety Effects In Animals
Acute
Kleinman (2020)
Nose-Only Exposure to Cherry- and Tobacco-Flavored E-Cigarettes Induced Lung Inflammation in Mice in a Sex-Dependent Manner.
Nonclinical
Safety Effects In Animals
Acute
Lamb (2022)
Exposure to nicotine-free and flavor-free e-cigarette vapors modifies the pulmonary response to tobacco cigarette smoke in female mice.
Nonclinical
Safety Effects In Animals
Non-Clinical Nicotine & Cotinine
Lechasseur (2020)
Biological changes in C57BL/6 mice following 3 weeks of inhalation exposure to cigarette smoke or e-vapor aerosols
Non-Clinical
Safety Effects In Animals
Repeat-dose Toxicity
Lee (2018)
Vapors Produced by Electronic Cigarettes and E-Juices with Flavorings Induce Toxicity, Oxidative Stress, and Inflammatory Response in Lung Epithelial Cells and in Mouse Lung
Non-Clinical
Safety Effects In Animals
Lerner (2015)
Electronic cigarette aerosols induce oxidative stress-dependent cell death and NF-κB mediated acute lung inflammation in mice.
Nonclinical
Safety Effects In Animals
Acute
Ma (2021)
Impact of electronic cigarette vaping on the cytoarchitecture of the tongue in the adult male albino rat.
Nonclinical
Safety Effects In Animals
Acute
Mandour (2022)
MaTERNaL NICOTINE EXPOSURE DURING GESTaTION aND LaCTaTION OF RaTS INDUCE MICROSCOPIC EMPhYSEMa IN ThE OFFSPRING
Non-Clinical
Safety Effects In Animals
Repeat-dose Toxicity
Maritz (2002)
Comparison of the cardiac effects of electronic cigarette aerosol exposure with waterpipe and combustible cigarette smoke exposure in rats.
Population Clinical
Safety Effects In Animals
Repeat-dose
Mayyas (2020)