Effects of nicotine and ThC vapor inhalation administered by an electronic nicotine delivery system (ENDS) in male rats.
Nonclinical
Safety Effects In Animals
Repeat-dose
Javadi-Paydar (2019)
Vapor inhalation of cannabidiol (CBD) in rats.
Nonclinical
Safety Effects In Animals
Repeat-dose
Javadi-Paydar (2019)
Nicotine Exposure Via Electronic Cigarettes Significantly Impedes Biomechanical healing Properties of Tendon healing in a Rat Model.
Nonclinical
Safety Effects In Animals
Repeat-dose
Kennedy (2021)
Transgenic chinese hamster V79 cell lines which exhibit variable levels of gpt mutagenesis
Non-Clinical
Safety Effects In Animals
Klein and Rossman (1990)
E-cigarette or Vaping Product Use-associated Lung Injury Produced in an animal Model From Electronic Cigarette Vapor Exposure Without Tetrahydrocannabinol or Vitamin E Oil.
Nonclinical
Safety Effects In Animals
Acute
Kleinman (2020)
Nose-Only Exposure to Cherry- and Tobacco-Flavored E-Cigarettes Induced Lung Inflammation in Mice in a Sex-Dependent Manner.
Nonclinical
Safety Effects In Animals
Acute
Lamb (2022)
Exposure to nicotine-free and flavor-free e-cigarette vapors modifies the pulmonary response to tobacco cigarette smoke in female mice.
Nonclinical
Safety Effects In Animals
Non-Clinical Nicotine & Cotinine
Lechasseur (2020)
Biological changes in C57BL/6 mice following 3 weeks of inhalation exposure to cigarette smoke or e-vapor aerosols
Non-Clinical
Safety Effects In Animals
Repeat-dose Toxicity
Lee (2018)
Vapors Produced by Electronic Cigarettes and E-Juices with Flavorings Induce Toxicity, Oxidative Stress, and Inflammatory Response in Lung Epithelial Cells and in Mouse Lung
Non-Clinical
Safety Effects In Animals
Lerner (2015)
Electronic cigarette aerosols induce oxidative stress-dependent cell death and NF-κB mediated acute lung inflammation in mice.
Nonclinical
Safety Effects In Animals
Acute
Ma (2021)