Developmental Neurotoxicity of Tobacco Smoke Directed Toward Cholinergic and Serotonergic Systems: More Than Just Nicotine
Nonclinical
Safety Effects In Animals
Acute Exposre
Slotkin (2015)
Short-term exposure of female BaLB/cJ mice to e-cigarette aerosol promotes neutrophil recruitment and enhances neutrophil-platelet aggregation in pulmonary microvasculature.
Nonclinical
Safety Effects In Animals
Acute Exposure
Snoderly (2023)
Electronic-cigarette smoke induces lung adenocarcinoma and bladder urothelial hyperplasia in mice.
Nonclinical
Safety Effects In Animals
Repeat-dose
Tang (2019)
Retinal tissue develops an inflammatory reaction to tobacco smoke and electronic cigarette vapor in mice.
Nonclinical
Safety Effects In Animals
Repeat-dose
Wang (2021)
Flavor-specific enhancement of electronic cigarette liquid consumption and preference in mice.
Nonclinical
Safety Effects In Animals
Non-Clinical Of Nicotine & Cotinine
Wong (2020)
Electronic Nicotine Vapor Exposure Produces Differential Changes in Central amygdala Neuronal activity, Thermoregulation and Locomotor Behavior in Male Mice.
Nonclinical
Safety Effects In Animals
Repeat-dose
Zhu (2021)
Impact of tobacco flavoring on oral nicotine consumption in C57BL/6J mice.
Nonclinical
Safety Effects In Animals
akinola (2022)
Time course of changes in inflammatory and oxidative biomarkers in lung tissue of mice induced by exposure to electronic cigarette aerosol.
Nonclinical
Safety Effects In Animals
alzoubi (2022)
animal Models to Investigate the Impact of Flavors on Nicotine addiction and Dependence.
Nonclinical
Safety Effects In Animals
Bagdas (2022)
Chronic oral nicotine exposure decreases aversive taste of nicotine, increases nicotine withdrawal and reinstatement, but cherry flavor does not alter nicotine’s effects in adolescent rats.
Nonclinical
Safety Effects In Animals
Non-Clinical Of Nicotine & Cotinine
Bagdas (2023)