Lasting effects of repeated ∆9 -tetrahydrocannabinol vapour inhalation during adolescence in male and female rats.
Nonclinical
Safety Effects In Animals
Repeat-dose
Nguyen (2020)
Electronic Cigarette Liquid Constituents Induce Nasal and Tracheal Sensory Irritation in Mice in Regionally Dependent Fashion.
Nonclinical
Safety Effects In Animals
Non-Clinical Of Nicotine & Cotinine
Ni (2020)
Changes in Eustachian Tube Mucosa in Mice after Short-Term Tobacco and E-cigarette Smoke Exposure.
Nonclinical
Safety Effects In Animals
Acute
Nicholas (2022)
E-cigarette aerosol impairs male mouse skeletal muscle force development and prevents recovery from injury.
Nonclinical
Safety Effects In Animals
Repeat-dose
Nogueira (2022)
Effects of Chronic Nicotine Inhalation on Systemic and Pulmonary Blood Pressure and Right Ventricular Remodeling in Mice.
Nonclinical
Safety Effects In Animals
Repeat-dose
Oakes (2020)
Evaluation of the Tobacco heating System 2.2. Part 6: 90-day OECD 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects of a mentholated version compared with mentholated and non-mentholated cigarette smoke
Non-Clinical
Safety Effects In Animals
Repeat-dose Toxicity
Oviedo (2016)
Strawberry additive Increases Nicotine Vapor Sampling and Systemic Exposure But Does Not Enhance Pavlovian-Based Nicotine Reward in Mice.
Nonclinical
Safety Effects In Animals
Repeat-dose
Patten (2023)
Increased sensitivity to D9-ThC-induced rewarding effects after seven-week exposure to electronic and tobacco cigarettes in mice.
Nonclinical
Safety Effects In Animals
Non-Clinical Of Nicotine & Cotinine
Ponzoni (2019)
Exposure to e-cigarette aerosol over two months induces accumulation of neurotoxic metals and alteration of essential metals in mouse brain.
Nonclinical
Safety Effects In Animals
Repeat-dose
Re (2021)
Metabolomics-based safety evaluation of acute exposure to electronic cigarettes in mice.
Nonclinical
Safety Effects In Animals
Acute Exposure
Ren (2022)