E-vapor aerosols do not compromise bone integrity relative to cigarette smoke after 6-month inhalation in an apoE-/- mouse model.
Nonclinical
Safety Effects In Animals
Repeat-dose
Reumann (2020)
Prenatal nicotine increases pulmonary α7 nicotinic receptor expression and alters fetal lung development in monkeys
Non-Clinical
Safety Effects In Animals
Non-Clinical
Of Nicotine &
Cotinine
Sekhon (1999)
a mouse model for chronic intermittent electronic cigarette exposure exhibits nicotine pharmacokinetics resembling human vapers.
Nonclinical
Safety Effects In Animals
Repeat-dose
Shao (2019)
One acute Exposure to E-Cigarette Smoke Using Various heating Elements and Power Levels Induces Pulmonary Inflammation.
Nonclinical
Safety Effects In Animals
Acute Exposre
Shi (2022)
Developmental Neurotoxicity of Tobacco Smoke Directed Toward Cholinergic and Serotonergic Systems: More Than Just Nicotine
Nonclinical
Safety Effects In Animals
Acute Exposre
Slotkin (2015)
Short-term exposure of female BaLB/cJ mice to e-cigarette aerosol promotes neutrophil recruitment and enhances neutrophil-platelet aggregation in pulmonary microvasculature.
Nonclinical
Safety Effects In Animals
Acute Exposure
Snoderly (2023)
Electronic-cigarette smoke induces lung adenocarcinoma and bladder urothelial hyperplasia in mice.
Nonclinical
Safety Effects In Animals
Repeat-dose
Tang (2019)
Retinal tissue develops an inflammatory reaction to tobacco smoke and electronic cigarette vapor in mice.
Nonclinical
Safety Effects In Animals
Repeat-dose
Wang (2021)
Flavor-specific enhancement of electronic cigarette liquid consumption and preference in mice.
Nonclinical
Safety Effects In Animals
Non-Clinical Of Nicotine & Cotinine
Wong (2020)
Electronic Nicotine Vapor Exposure Produces Differential Changes in Central amygdala Neuronal activity, Thermoregulation and Locomotor Behavior in Male Mice.
Nonclinical
Safety Effects In Animals
Repeat-dose
Zhu (2021)